AustralieFrV1, Main, Exploration, bibRecord, 009714

Association of glucose metabolism, smoking and cardiovascular risk factors with incident peripheral arterial disease : The DESIR study

Identifieur interne : 009714 ( Main/Exploration ); précédent : 009713; suivant : 009715

Association of glucose metabolism, smoking and cardiovascular risk factors with incident peripheral arterial disease : The DESIR study

Auteurs : Robyn J. Tapp [France, Australie] ; Beverley Balkau [France] ; Jonathan E. Shaw [Australie] ; Paul Valensi [France] ; Martine Cailleau [France] ; Eveline Eschwege [France]

Source :

Atherosclerosis [ 0021-9150 ] ; 2007.

RBID : Pascal:07-0335594

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Diabète de type 2 (métabolisme), Diabète de type 2 (épidémiologie), Facteurs de risque, Femelle, France (épidémiologie), Glucose (métabolisme), Humains, Incidence, Insulinorésistance, Intolérance au glucose (métabolisme), Intolérance au glucose (épidémiologie), Maladies vasculaires périphériques (métabolisme), Maladies vasculaires périphériques (épidémiologie), Modèles logistiques, Mâle, Sujet âgé, Tabagisme (métabolisme), Tabagisme (épidémiologie), Études longitudinales, Évolution de la maladie.
MESH :
- métabolisme : Diabète de type 2, Glucose, Intolérance au glucose, Maladies vasculaires périphériques, Tabagisme.
- épidémiologie : Diabète de type 2, France, Intolérance au glucose, Maladies vasculaires périphériques, Tabagisme.
Pascal (Inist)
- Adulte, Adulte d'âge moyen, Appareil circulatoire pathologie, Athérosclérose, Facteurs de risque, Femelle, Humains, Incidence, Insulinorésistance, Modèles logistiques, Mâle, Sujet âgé, Tabagisme, Artériopathie oblitérante, Diabète, Glucose, Métabolisme, Facteur risque, Incidence, Epidémiologie, Insuline, Jeûne alimentaire, Diagnostic, Claudication, Cholestérol, Triglycéride, Conduite à tenir, Études longitudinales, Évolution de la maladie.
Wicri :
- geographic : France.
- topic : Tabagisme, Diabète, Glucose.

English descriptors

KwdEn :
- Adult, Aged, Atherosclerosis, Cardiovascular disease, Cholesterol, Claudication, Clinical management, Diabetes Mellitus, Type 2 (epidemiology), Diabetes Mellitus, Type 2 (metabolism), Diabetes mellitus, Diagnosis, Disease Progression, Epidemiology, Fasting, Female, France (epidemiology), Glucose, Glucose (metabolism), Glucose Intolerance (epidemiology), Glucose Intolerance (metabolism), Humans, Incidence, Insulin, Insulin Resistance, Logistic Models, Longitudinal Studies, Male, Metabolism, Middle Aged, Occlusive arterial disease, Peripheral Vascular Diseases (epidemiology), Peripheral Vascular Diseases (metabolism), Risk Factors, Risk factor, Smoking (epidemiology), Smoking (metabolism), Tobacco smoking, Triglyceride.
MESH :
- chemical , metabolism : Glucose.
- geographic , epidemiology : France.
- epidemiology : Diabetes Mellitus, Type 2, Glucose Intolerance, Peripheral Vascular Diseases, Smoking.
- metabolism : Diabetes Mellitus, Type 2, Glucose Intolerance, Peripheral Vascular Diseases, Smoking.
- Adult, Aged, Disease Progression, Female, Humans, Incidence, Insulin Resistance, Logistic Models, Longitudinal Studies, Male, Middle Aged, Risk Factors.

Abstract

Aims: We determined the 6-year incidence of peripheral arterial disease (PAD) in a French population and assessed the association of glucose metabolism, smoking, cardiovascular risk factors and physical activity with incident PAD. Methods: Participants from the French Data from a Epidemiological Study on the Insulin Resistance Syndrome (DESIR) were studied. Participants analysed were 30-65 years (at baseline) and had complete data (n = 3805) after 6 years of follow-up. Diabetes was diagnosed according to the 1999 WHO criteria on the basis of fasting plasma glucose results or previous diagnosis of diabetes mellitus. The ankle brachial pressure index (ABPI) and a claudication question were used to classify PAD. Results: The 6-year incidence of PAD (defined by ABPI < 0.9 and or claudication present) among those with normal fasting glucose (NFG) and free of PAD at baseline was 5.1%. Among those with impaired fasting glucose (IFG) at baseline the incidence of PAD was 4.9% and among those with diabetes mellitus at baseline the incidence of PAD was 9.8%. The incidence of PAD among those who maintained NFG over 6 years was 4.7% and among those who progressed to diabetes over 6 years was 10.2%. Those who progressed from NFG or IFG to diabetes over 6 years were twice as likely to develop PAD compared to those who maintained NFG over 6 years, after adjustment for age and sex (OR (95% CI), 2.22 (1.12-4.42)). Independent risk factors for incident PAD using baseline population characteristics were diabetes (OR (95% CI) 2.11 (1.25-3.55)), systolic BP 122-135 mmHg 1.06 (0.70-1.60), >135mmHg 1.54 (1.04-2.27) and current smoking 1.60 (1.10-2.34) after multivariate adjustment for age, sex, cholesterol, triglycerides and waist circumference. Conclusions: This French study shows that those who progress to diabetes are twice as likely to develop PAD, compared to those who maintain NFG. Peripheral arterial disease is a treatable condition and more aggressive management of atherosclerotic risk factors could reduce the numbers of people who develop PAD.

Affiliations:

Le document en format XML

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<series><title level="j" type="main">Atherosclerosis</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Atherosclerosis</term>
<term>Cardiovascular disease</term>
<term>Cholesterol</term>
<term>Claudication</term>
<term>Clinical management</term>
<term>Diabetes Mellitus, Type 2 (epidemiology)</term>
<term>Diabetes Mellitus, Type 2 (metabolism)</term>
<term>Diabetes mellitus</term>
<term>Diagnosis</term>
<term>Disease Progression</term>
<term>Epidemiology</term>
<term>Fasting</term>
<term>Female</term>
<term>France (epidemiology)</term>
<term>Glucose</term>
<term>Glucose (metabolism)</term>
<term>Glucose Intolerance (epidemiology)</term>
<term>Glucose Intolerance (metabolism)</term>
<term>Humans</term>
<term>Incidence</term>
<term>Insulin</term>
<term>Insulin Resistance</term>
<term>Logistic Models</term>
<term>Longitudinal Studies</term>
<term>Male</term>
<term>Metabolism</term>
<term>Middle Aged</term>
<term>Occlusive arterial disease</term>
<term>Peripheral Vascular Diseases (epidemiology)</term>
<term>Peripheral Vascular Diseases (metabolism)</term>
<term>Risk Factors</term>
<term>Risk factor</term>
<term>Smoking (epidemiology)</term>
<term>Smoking (metabolism)</term>
<term>Tobacco smoking</term>
<term>Triglyceride</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Diabète de type 2 (métabolisme)</term>
<term>Diabète de type 2 (épidémiologie)</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>France (épidémiologie)</term>
<term>Glucose (métabolisme)</term>
<term>Humains</term>
<term>Incidence</term>
<term>Insulinorésistance</term>
<term>Intolérance au glucose (métabolisme)</term>
<term>Intolérance au glucose (épidémiologie)</term>
<term>Maladies vasculaires périphériques (métabolisme)</term>
<term>Maladies vasculaires périphériques (épidémiologie)</term>
<term>Modèles logistiques</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Tabagisme (métabolisme)</term>
<term>Tabagisme (épidémiologie)</term>
<term>Études longitudinales</term>
<term>Évolution de la maladie</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Glucose</term>
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</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Diabetes Mellitus, Type 2</term>
<term>Glucose Intolerance</term>
<term>Peripheral Vascular Diseases</term>
<term>Smoking</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Diabetes Mellitus, Type 2</term>
<term>Glucose Intolerance</term>
<term>Peripheral Vascular Diseases</term>
<term>Smoking</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Diabète de type 2</term>
<term>Glucose</term>
<term>Intolérance au glucose</term>
<term>Maladies vasculaires périphériques</term>
<term>Tabagisme</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Diabète de type 2</term>
<term>France</term>
<term>Intolérance au glucose</term>
<term>Maladies vasculaires périphériques</term>
<term>Tabagisme</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Incidence</term>
<term>Insulin Resistance</term>
<term>Logistic Models</term>
<term>Longitudinal Studies</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Risk Factors</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Appareil circulatoire pathologie</term>
<term>Athérosclérose</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Incidence</term>
<term>Insulinorésistance</term>
<term>Modèles logistiques</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Tabagisme</term>
<term>Artériopathie oblitérante</term>
<term>Diabète</term>
<term>Glucose</term>
<term>Métabolisme</term>
<term>Facteur risque</term>
<term>Incidence</term>
<term>Epidémiologie</term>
<term>Insuline</term>
<term>Jeûne alimentaire</term>
<term>Diagnostic</term>
<term>Claudication</term>
<term>Cholestérol</term>
<term>Triglycéride</term>
<term>Conduite à tenir</term>
<term>Études longitudinales</term>
<term>Évolution de la maladie</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>France</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Tabagisme</term>
<term>Diabète</term>
<term>Glucose</term>
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<front><div type="abstract" xml:lang="en">Aims: We determined the 6-year incidence of peripheral arterial disease (PAD) in a French population and assessed the association of glucose metabolism, smoking, cardiovascular risk factors and physical activity with incident PAD. Methods: Participants from the French Data from a Epidemiological Study on the Insulin Resistance Syndrome (DESIR) were studied. Participants analysed were 30-65 years (at baseline) and had complete data (n = 3805) after 6 years of follow-up. Diabetes was diagnosed according to the 1999 WHO criteria on the basis of fasting plasma glucose results or previous diagnosis of diabetes mellitus. The ankle brachial pressure index (ABPI) and a claudication question were used to classify PAD. Results: The 6-year incidence of PAD (defined by ABPI < 0.9 and or claudication present) among those with normal fasting glucose (NFG) and free of PAD at baseline was 5.1%. Among those with impaired fasting glucose (IFG) at baseline the incidence of PAD was 4.9% and among those with diabetes mellitus at baseline the incidence of PAD was 9.8%. The incidence of PAD among those who maintained NFG over 6 years was 4.7% and among those who progressed to diabetes over 6 years was 10.2%. Those who progressed from NFG or IFG to diabetes over 6 years were twice as likely to develop PAD compared to those who maintained NFG over 6 years, after adjustment for age and sex (OR (95% CI), 2.22 (1.12-4.42)). Independent risk factors for incident PAD using baseline population characteristics were diabetes (OR (95% CI) 2.11 (1.25-3.55)), systolic BP 122-135 mmHg 1.06 (0.70-1.60), >135mmHg 1.54 (1.04-2.27) and current smoking 1.60 (1.10-2.34) after multivariate adjustment for age, sex, cholesterol, triglycerides and waist circumference. Conclusions: This French study shows that those who progress to diabetes are twice as likely to develop PAD, compared to those who maintain NFG. Peripheral arterial disease is a treatable condition and more aggressive management of atherosclerotic risk factors could reduce the numbers of people who develop PAD.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>France</li>
</country>
<region><li>Victoria (État)</li>
</region>
<settlement><li>Melbourne</li>
</settlement>
</list>
<tree><country name="France"><noRegion><name sortKey="Tapp, Robyn J" sort="Tapp, Robyn J" uniqKey="Tapp R" first="Robyn J." last="Tapp">Robyn J. Tapp</name>
</noRegion>
<name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name>
<name sortKey="Cailleau, Martine" sort="Cailleau, Martine" uniqKey="Cailleau M" first="Martine" last="Cailleau">Martine Cailleau</name>
<name sortKey="Eschwege, Eveline" sort="Eschwege, Eveline" uniqKey="Eschwege E" first="Eveline" last="Eschwege">Eveline Eschwege</name>
<name sortKey="Valensi, Paul" sort="Valensi, Paul" uniqKey="Valensi P" first="Paul" last="Valensi">Paul Valensi</name>
</country>
<country name="Australie"><noRegion><name sortKey="Tapp, Robyn J" sort="Tapp, Robyn J" uniqKey="Tapp R" first="Robyn J." last="Tapp">Robyn J. Tapp</name>
</noRegion>
<name sortKey="Shaw, Jonathan E" sort="Shaw, Jonathan E" uniqKey="Shaw J" first="Jonathan E." last="Shaw">Jonathan E. Shaw</name>
<name sortKey="Shaw, Jonathan E" sort="Shaw, Jonathan E" uniqKey="Shaw J" first="Jonathan E." last="Shaw">Jonathan E. Shaw</name>
</country>
</tree>
</affiliations>
</record>

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{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:07-0335594
   |texte=   Association of glucose metabolism, smoking and cardiovascular risk factors with incident peripheral arterial disease : The DESIR study
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

Association of glucose metabolism, smoking and cardiovascular risk factors with incident peripheral arterial disease : The DESIR study

Association of glucose metabolism, smoking and cardiovascular risk factors with incident peripheral arterial disease : The DESIR study

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Abstract

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	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.